Leeds Institute of Cancer and Pathology

Pre-Cancer Genomics

Henry Wood – Senior Research Fellow

Contact Information

Dr Henry Wood
Section of Pre-Cancer Genomics
Leeds Institute of Cancer and Pathology
Wellcome Trust Brenner Building
St James’s University Hospital
LS9 7TF, Leeds
United Kingdom

tel: +44 (0) 113 2064070
email: h.m.wood@leeds.ac.uk

 

 

 

Role

As well as my own research, I am involved in the management and development of all the research activity in the Pre-Cancer Genomics group, with particular responsibility for bridging the gap between the wet lab scientists and the bioinformatic analysts.

Research

I am interested in developing methods to study whole genomes to solve biological problems. In particular I am working on using next-generation sequencing technology to look at tumour progression. I am interested both in new laboratory techniques and computational methods that will allow the nature of tumour and pre-cancer genomes to be more thoroughly examined. As part of my belief that examining the entire genomes of as many patients as possible is essential to understanding the nature of disease, I have developed methods to examine genomic copy number from small clinical specimens at high levels of multiplexing.

My background is as a lab scientist using whole genome genetic fingerprinting techniques to look for regions of interest in evolving traits in non-model organisms, and then sequencing those regions using phage and BAC libraries. I have transferred those skills picked up working on ‘difficult’ samples to enable me to study the complex genetics of cancer biology.

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