Leeds Institute of Cancer and Pathology

Pre-Cancer Genomics

Software and Datasets


CNAnorm – an R package to perform normalisation of copy number from next generation sequence data, taking into account tumour cell content and possible aneuploid genome size.

GH-index – R code to use with CNAnorm to calculate G-stat, H-stat and GH index from copy number data.

PRISMAD – Polymorphism Rates Indicate Somatic Mutations As Drivers. A tool for annotating genes as candidates for harbouring somatic driver mutations. The scripts and data used for this software are available here.


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